| Rochester Lady Lancers | — | — | 2017 | Marina Auto Stadium |
| Rochester Lancers | North American Soccer League | Rochester | 1967 | Holleder Memorial Stadium |
| Rochester Lancers | — | Rochester | 2015 | — |
| Rochester Lancers | Major Indoor Soccer League | — | 2010 | Blue Cross Arena |
| Rochester Med City FC | National Premier Soccer League | Rochester | — | — |
| Rochester Ravens | USL W-League | — | 2003 | — |
| Rochester Rhinos | — | Rochester | 1996 | John L. DiMarco Field, Marina Auto Stadium, ESL Ballpark |
| Rochester Thunder | USL League Two | — | 2008 | — |
| Rocket City United | National Premier Soccer League | — | 2007 | — |
| Rockford Rampage | Major Arena Soccer League | — | 2005 | Victory Sports Complex |
| RVA FC | National Premier Soccer League | Fredericksburg | 2013 | Sports Backers Stadium |
| RWB Adria | United Premier Soccer League | Chicago | 1959 | — |
| Sacramento Geckos | USL Second Division | Sacramento | 1997 | — |
| Sacramento Gold FC | National Premier Soccer League | — | 2009 | — |
| Sacramento Knights | Continental Indoor Soccer League | — | 1993 | ARCO Arena |
| Sacramento Knights | National Premier Soccer League | — | 2003 | Folsom High School |
| Sacramento Pride | Women's Premier Soccer League | — | 2001 | — |
| Sacramento Republic FC | USL Championship | Sacramento | December 3, 2012 | Heart Health Park |
| Sacramento Surge | Major Arena Soccer League | — | 2012 | — |
| Salem City FC | USL League Two | Greensboro | 1993 | Macpherson Stadium |
| Salinas Valley Samba | National Premier Soccer League | — | 2004 | Watsonville High School |
| San Antonio Pumas | — | — | 1988 | — |
| San Antonio Scorpions | North American Soccer League | — | 2010 | Toyota Field |
| San Antonio Thunder | North American Soccer League | — | 1975 | Alamo Stadium |
| San Diego 1904 FC | National Independent Soccer Association | San Diego | 2017 | Torero Stadium |
| San Diego Boca F.C. | National Premier Soccer League | — | 2009 | Balboa Stadium |
| San Diego FC | Major League Soccer | San Diego | May 18, 2023 | Snapdragon Stadium |
| San Diego Flash | A-League, National Premier Soccer League | San Diego | 1998 | Mira Mesa Senior High School |
| San Diego Gauchos | USL League Two | — | 2002 | Torero Stadium |
| San Diego Jaws | North American Soccer League | San Diego | 1976 | Aztec Bowl |
| San Diego Loyal SC | USL Championship | San Diego | 2019 | Torero Stadium |
| San Diego Pumitas | National Premier Soccer League | — | 1999 | Balboa Stadium |
| San Diego Sockers | North American Soccer League | San Diego | 1978 | San Diego Stadium |
| San Diego Sockers | Major Arena Soccer League | San Diego | 2009 | Pechanga Arena |
| San Diego Sockers 2 | — | — | 2017 | Pechanga Arena |
| San Diego Top Guns | — | San Diego | 1994 | — |
| San Diego Toros | North American Soccer League | San Diego | 1966 | Balboa Stadium |
| San Diego United | National Premier Soccer League | — | 2008 | Torero Stadium |
| San Diego Wave FC | National Women's Soccer League | San Diego | June 8, 2021 | Snapdragon Stadium, Torero Stadium |
| San Diego Zest FC | USL League Two | San Diego | 2016 | RIMAC Sports Complex |
| San Diego Zest FC Women | Women's Premier Soccer League | — | 2017 | — |
| San Francisco Bay Blackhawks | — | — | 1989 | CEFCU Stadium |
| San Francisco Bay Diablos | — | San Francisco | 1993 | — |
| San Francisco City FC | USL League Two | San Francisco | 2001 | Negoesco Stadium |
| San Francisco Deltas | North American Soccer League | San Francisco | 2016 | Kezar Stadium |
| San Francisco Fog | — | — | 1980 | Cow Palace |
| San Francisco Glens | USL League Two | San Francisco | 1961 | Boxer Stadium |
| San Francisco Golden Gate Gales | — | San Francisco | 1967 | Candlestick Park |