| Brownsville Barracudas | Major Arena Soccer League | — | 2014 | Payne Arena |
| Buffalo City FC | National Premier Soccer League | — | 2008 | Nichols School |
| Buffalo FFillies | — | Buffalo | 1996 | — |
| Buffalo Pro Soccer | USL Super League, USL Championship | Buffalo | 2024 | Queen City Field |
| Buffalo Stallions | Major Indoor Soccer League | Buffalo | 1979 | Buffalo Memorial Auditorium |
| Burlingame Dragons FC | USL League Two | Burlingame | 2014 | Burlingame High School |
| Buxmont Torch FC | National Premier Soccer League | Perkasie | 2010 | Christopher Dock Mennonite High School |
| Caguas Sporting FC | Puerto Rico Soccer League | — | 2016 | — |
| Cal FC | United States Adult Soccer Association | — | 2009 | Agoura High School |
| Caledonia SC | USL League Two | Lakeland | January 12, 2022 | — |
| California Cougars | Major Arena Soccer League | — | 2004 | Adventist Health Arena |
| California Gold | USL League Two | — | 2002 | — |
| California Jaguars | USL Championship | — | 1995 | Salinas Sports Complex |
| California Storm | Women's Premier Soccer League | — | 1995 | — |
| California Sunshine | — | Fountain Valley | 1977 | — |
| California Surf | North American Soccer League | Anaheim | 1978 | Angel Stadium of Anaheim |
| California United Strikers FC | National Independent Soccer Association | Fullerton | 2017 | Titan Stadium |
| Cape Cod Crusaders | USL League Two | Massachusetts | 1994 | Massachusetts Maritime Academy |
| Cape Coral Hurricanes | National Premier Soccer League | — | 2010 | Cape Coral High School |
| Carolina Ascent FC | USL Super League | Charlotte | — | — |
| Carolina Core FC | MLS Next Pro | High Point | 2022 | Truist Point |
| Carolina Courage | Women's United Soccer Association | Cary | 2001 | WakeMed Soccer Park |
| Carpathia FC | United Premier Soccer League | — | 1952 | — |
| Cars Plus FC | Guam Men's Soccer League | Guam | — | — |
| Cary Lady Clarets | USL W-League | — | 2007 | WakeMed Soccer Park |
| Cascade Surge | USL League Two | — | 1995 | McCulloch Stadium |
| CASL Elite | Capital Area Soccer League | — | 2009 | WakeMed Soccer Park |
| CD Aguiluchos USA | National Premier Soccer League | Oakland | 2012 | — |
| Cedar Rapids Rampage United | United Premier Soccer League | — | 2016 | — |
| Central Coast Roadrunners | USL League Two | San Luis Obispo | 1996 | Mustang Memorial Field |
| Central SC Cobras | USL W-League | — | 2010 | — |
| CF Montréal | Major League Soccer | Montreal | 2010 | Saputo Stadium |
| Charleston Battery | USL Championship | Charleston | 1993 | MUSC Health Stadium |
| Charlotte Eagles | USL League Two | Charlotte | 1991 | Sportsplex at Matthews |
| Charlotte FC | Major League Soccer | Charlotte | December 17, 2019 | Bank of America Stadium |
| Charlotte Independence | USL Championship, USL League One | Charlotte | 2014 | Sportsplex at Matthews |
| Charlotte Independence Soccer Club | USL League Two | Rock Hill | — | Manchester Meadows Soccer Complex |
| Charlotte Lady Eagles | USL W-League | — | 2003 | — |
| Charlottesville Alliance FC | National Premier Soccer League | Charlottesville | 2016 | Charlottesville High School |
| Charm City FC | National Premier Soccer League | — | 2007 | Arundel High School |
| Chattanooga Red Wolves SC | USL League One | Chattanooga | August 1, 2018 | Chattanooga Christian School |
| Chesapeake Dragons | USL League Two | — | 2001 | Maryland SoccerPlex |
| Chesterfield United FC | National Premier Soccer League | — | 2013 | Williams Stadium |
| Chicago Cats | — | Chicago | 1975 | — |
| Chicago Croatian | National Soccer League | Chicago | 1949 | — |
| Chicago Fire FC | Major League Soccer | Chicago | October 8, 1997 | Soldier Field |
| Chicago Fire NPSL | National Premier Soccer League | — | 2007 | SeatGeek Stadium |
| Chicago Fire U-23 | USL League Two | — | 2001 | SeatGeek Stadium |